– In vitro skin corrosion test (OECD TG431);

– In vitro skin irritation test (OECD TG439 and ISO 10993-23:2021);

– In vitro eye irritation test – HET CAM (ICCVAM);

– In vitro vaginal irritation test (SOP Mattec Epivaginal);

– In vitro skin permeation test – Franz cells or Ussing chambers – animal model or synthetic membrane (OECD TG428; USP38);

– In vitro mutagenicity test – Ames test (OECD 471);

– In vitro genotoxicity test – micronuclei (OECD TG487);

– In vitro cytotoxicity test (ISO 10993-5);

– In vitro phototoxicity test 3T3 Neutral Red Uptake (OECD 432);